PREVALENCE OF BRCA HOMOPOLYMERIC INDELS IN AN ION TORRENT-BASED TUMOUR-TO-GERMLINE TESTING WORKFLOW IN HIGH-GRADE OVARIAN CARCINOMA

Prevalence of BRCA homopolymeric indels in an ION Torrent-based tumour-to-germline testing workflow in high-grade ovarian carcinoma

Abstract Tumour DNA sequencing is essential for precision medicine since it guides therapeutic decisions but also fosters the identification of patients who may benefit from germline testing.Notwithstanding, the tumour-to-germline testing workflow presents a few caveats.The low sensitivity for indels at loci with sequences of identical bases (homop

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El Oriente Medio en el contexto monetario internacional

El propósito de este artículo es el de describir y analizar cómo el ensayo de la estrategia de desarrollo y de reconstrucción de las economías occidentales, lideradas por los Estados Unidos después de la II tonic shower cap Guerra Mundial, al crear en 1945 el Sistema Monetario Financiero integrado por el Fo

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Investigation on energy dissipation mechanism in a double-suction centrifugal pump based on Rortex and enstrophy

Since double-suction centrifugal pumps consume quantities of energy, revealing critical factors for energy dissipation is helpful for energy-saving design.This study aims to investigate the relationship tonic shower cap between energy dissipation and vortex based on Rortex method in a double-suction centrifugal pump.Detached eddy simulation was app

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A Phylogenetic Morphometric Investigation of Interspecific Relationships of Lyponia s. str. (Coleoptera, Lycidae) Based on Male Genitalia Shapes

The nominate subgenus Lyponia Waterhouse, 1878 from China is reviewed, with two new species described and named L.(s.str.) ruficeps sp.n.(China, Yunnan) and L.(s.str.) zayuana sp.n.(China, Xizang).A distribution map and a key to all species of Lyponia s.str.are provided.Moreover, the phenotypic relationships rk559 among the species of Lyponia s.str

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